Through our partnership with Infusion Associates, we have a dedicated research department, including physicians, certified nurse coordinators, nurse practitioners, and pharmacists. We collaborate with pharmaceutical companies and local specialists to offer new study treatment opportunities for our patients.
If you decide to participate in a clinical trial with us, know that our study team is dedicated to study-related care and communication throughout the duration of the trial – and after. Although our goal is to forward research, so is ensuring our participants feel comfortable and well taken care of.
Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) Study
Novartis’ CAIN study is an open-label, multi-center study to evaluate the pharmacokinetics, safety and tolerability of the intravenous secukinumab infusion in adults with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Patients 50 years of age or older who have experienced GCA or PMR actively in the last six months may be eligible to participate in this open-label study. This study will consist of three phases: screening and study treatment occupying 12 weeks, with an 8-week follow-up period. Eligible participants may be reimbursed for time and travel in the study.
Who can participate in the CAIN Study?
Giant Cell Arteritis (GCA) Criteria:
- Male or non-pregnant, non-lactating female participants 50+ years of age
- Diagnosis of GCA based on meeting required criteria
- Active GCA disease within 6 months prior to study as defined by: Signs or symptoms attributed to active GCA and not related to prior damage / Elevated ESR attributed to active GCA or active GCA on TAB or on imaging study
Polymyalgia Rheumatica (PMR) Criteria:
- Male or non-pregnant, non-lactating female participants 50+ years of age
- Diagnosis of PMR according to the provisional ACR/EULAR classification criteria
- Active PMR disease within 6 months prior to the study as defined by: Bilateral shoulder girdle and/or bilateral hip girdle and/or bilateral hip gridle and/or bilateral hip girdle pain indicative of a PMR relapse
